Liesbeth Reneman

Developmental Neuropsychopharmacology and Brainimaging group

Focus of research:

The Developmental Neuropsychopharmacology and Brainimaging group aims at unravelling the effects of drugs (of abuse) on the (developing) brain using a multidisciplinary approach and state-of-the-art neuroimaging techniques.

AMC themes: Neurological & Psychiatric Disorders
Departments: Radiology



Anne Marije Kaag

The role of the serotonergic system in the development and treatment of cocaine dependence

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Anouk Schrantee

Validating non-invasive imaging of the serotonergic and dopaminergic system and adult neurogenesis with MRI

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Cheima Bouziane

effects of psychotropic drugs on the developing brain (ePOD)

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Hyke Tamminga

effects of psychotropic drugs on the developing brain (ePOD)

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Maik Derksen

Validation of pharmacological MR imaging in awake rodents

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Marco Bottelier

Effects of methylphenidate on the developing brain”

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Martine van Doorn

NEOREST: rs-fMRI in term neonates with perinatal asphyxia

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Michiel de Ruiter

Neuroimaging of cognitive decline in cancer patients and cancer survivors

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Myrle Kemperman


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Sanne Menning

Structural, biochemical and functional indices of chemotherapy-induced cognitive deficits in breast cancer patients.

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Key publications

Bottelier MA, Schouw MLJ, Klomp A, Tamminga HGH, Schrantee AGM, Bouziane C, de Ruiter MB, Boer F, Ruhé HG , Denys D, Rijsman R, Lindauer RJL, Reitsma HB, Geurts HM, Reneman L, The effects of Psychotropic drugs On Developing brain (ePOD) study: methods and design. BMC PSYCHIATRY 2014;14 (1):48

van der Marel K, Klomp A, Meerhoff GF, Schipper P, Lucassen PJ, Homberg JR, Dijkhuizen RM, Reneman L, Long-term oral methylphenidate treatment in adolescent and adult rats: differential effects on brain morphology and function. NEUROPSYCHOPHARMACOL 2014;39 (2):263-273

Schouw MLJ, Kaag AM, Caan MWA, Heijtel DFR, Majoie CBLM, Nederveen AJ, Booij J, Reneman L, Mapping the hemodynamic response in human subjects to a dopaminergic challenge with dextroamphetamine using ASL-based pharmacological MRI. NEUROIMAGE 2013;72:1-9

Klomp A, Tremoleda JL, Wylezinska M, Nederveen AJ, Feenstra M, Gsell W, Reneman L, Lasting effects of chronic fluoxetine treatment on the late developing rat brain: age-dependent changes in the serotonergic neurotransmitter system assessed by pharmacological MRI. NEUROIMAGE 2012;59 (1):218-226

Reneman L, Booij J, de Bruin K, Reitsma JB, de Wolff FA, Gunning WB, den Heeten GJ, van den Brink W, Effects of dose, sex, and long-term abstention from use on toxic effects of MDMA (ecstasy) on brain serotonin neurons. LANCET 2001;358 (9296):1864-1869


List of Publications