Liesbeth Reneman

Developmental Neuropsychopharmacology and Brainimaging group

Focus of research:

The Developmental Neuropsychopharmacology and Brainimaging group aims at unravelling the effects of drugs (of abuse) on the (developing) brain using a multidisciplinary approach and state-of-the-art neuroimaging techniques.

AMC themes: Neurological & Psychiatric Disorders
Departments: Radiology



Anne Marije Kaag

The role of the serotonergic system in the development and treatment of cocaine dependence

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Anouk Schrantee

Validating non-invasive imaging of the serotonergic and dopaminergic system and adult neurogenesis with MRI

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Cheima Bouziane

effects of psychotropic drugs on the developing brain (ePOD)

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Hyke Tamminga

effects of psychotropic drugs on the developing brain (ePOD)

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Maik Derksen

Validation of pharmacological MR imaging in awake rodents

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Michiel de Ruiter

Neuroimaging of cognitive decline in cancer patients and cancer survivors

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Myrle Kemperman


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Sanne Menning

Structural, biochemical and functional indices of chemotherapy-induced cognitive deficits in breast cancer patients.

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Key publications

Klomp A, Tremoleda JL, Wylezinska M, Nederveen AJ, Feenstra M, Gsell W, Reneman L, Lasting effects of chronic fluoxetine treatment on the late developing rat brain: age-dependent changes in the serotonergic neurotransmitter system assessed by pharmacological MRI. NEUROIMAGE 2012;59 (1):218-226

de Ruiter MB, Reneman L, Boogerd W, Veltman DJ, Caan M, Douaud G, Lavini C, Linn SC, Boven E, van Dam FSAM, Schagen SB, Late effects of high-dose adjuvant chemotherapy on white and gray matter in breast cancer survivors: Converging results from multimodal magnetic resonance imaging. HUM BRAIN MAPP 2012;ahead of print

Homberg JR, Olivier JDA, Blom T, Arentsen T, van Brunschot C, Schipper P, Korte-Bouws G, van Luijtelaar G, Reneman L, Fluoxetine Exerts Age-Dependent Effects on Behavior and Amygdala Neuroplasticity in the Rat. PLOS ONE 2011;6 (1):e16646

Reneman L, Lavalaye J, Schmand B, de Wolff FA, van den Brink W, den Heeten GJ, Booij J, Cortical serotonin transporter density and verbal memory in individuals who stopped using 3,4-methylenedioxymethamphetamine (MDMA or “ecstasy”): preliminary findings. ARCH GEN PSYCHIAT 2001;58 (10):901-906

Reneman L, Booij J, de Bruin K, Reitsma JB, de Wolff FA, Gunning WB, den Heeten GJ, van den Brink W, Effects of dose, sex, and long-term abstention from use on toxic effects of MDMA (ecstasy) on brain serotonin neurons. LANCET 2001;358 (9296):1864-1869